Demonstrators march though Berlin, saying face masks and other measures violate their rights.
The demonstrators say the measures, including the wearing of facemasks, violate their rights and freedoms.
Germany has been less badly affected by the pandemic than some European countries, but cases are starting to rise again.
On Friday it recorded more than 900 new cases and seven deaths.
Official estimates say at least 15,000 people are taking part in the protests, which is being called “The Day of Freedom”.